The problem is that your Apache server is not compiled with rewrite module or you don't have rewrite instructions in your Dolphin's root .htaccess file. These instructions should be as follows:

<IfModule mod_rewrite.c>
RewriteEngine on
RewriteCond %{REQUEST_FILENAME} -f [OR]
RewriteCond %{REQUEST_FILENAME} -d
RewriteRule .+ - [L]
RewriteRule ^([A-Za-z0-9_-]+)$ profile.php?ID=$1 [QSA,L]
</IfModule>

see more If you can't solve these problems, you can disable Friendly profile permalinks in Settings -> Advanced Settings